Aiming at the problems of low accuracy and poor robustness of traditional point cloud registration algorithms and the inability of accurate radiotherapy for cancer patients before and after radiotherapy， an Attention Dynamic Graph Convolutional Neural Network Lucas-Kanade （ADGCNNLK） was proposed. Firstly， residual attention mechanism was added to Dynamic Graph Convolutional Neural Network （DGCNN） to effectively utilize spatial information of point cloud and reduce information loss. Then， the DGCNN added with residual attention mechanism was used to extract point cloud features， this process was not only able to capture the local geometric features of the point cloud while maintaining the invariance of the point cloud replacement， but also able to semantically aggregate the information， thereby improving the registration efficiency. Finally， the extracted feature points were mapped to a high-dimensional space， and the classic image iterative registration algorithm LK （Lucas-Kanade） was used for registration of the nodes. Experimental results show that compared with Iterative Closest Point （ICP）， Globally optimal ICP （Go-ICP） and PointNetLK， the proposed algorithm has the best registration effect with or without noise. Among them， in the case without noise， compared with PointNetLK， the proposed algorithm has the rotation mean squared error reduced by 74.61%， and the translation mean squared error reduced by 47.50%； in the case with noise， compared with PointNetLK， the proposed algorithm has the rotation mean squared error reduced by 73.13%， and the translational mean squared error reduced by 44.18%， indicating that the proposed algorithm is more robust than PointNetLK. And the proposed algorithm is applied to the registration of human point cloud models of cancer patients before and after radiotherapy， assisting doctors in treatment， and realizing precise radiotherapy.